3. Pharmacology
          3.1. Pharmacology principles
              3.1.3. Pharmacogenetics
                  3.1.3.3. Malignant hyperthermia
 3.1.3.3.1. Dantrolene

Dantrolene

 

 

Each bottle contains

Dantrolene 20mg

Mannitol 3g (solubilising agent)

 

Dosage 1mg/kg, up to 10mg/kg

Average requirement = 3mg/kg

 

Side effects include

N&V

Muscle weakness

Prolongation of non-depolarising NMBDs



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