Opioid Agonists & Antagonists

03A6
Explain how differences in the pharmacokinetics of alfentanil and fentanyl can influence the way they are administered intravenously.
51%

 

02B6
Write brief notes on tolerance and dependence in relation to opioid analgesics.
N/A

 

01B12
Outline the effects of an opioid injected into the spinal intrathecal space
18%

 

00B12
Explain how differences in the pharmacokinetics of alfentanil and fentanyl can influence the way they are administered intravenously
54%

 

00A15
Describe the effects of opioids on the respiratory system
75%

 

99A10
Write a brief outline on the pharmacology of remifentanil.
47%

 

98B11
Describe briefly the acute unwanted effects of the opioid agonist drugs
53%

1997
Briefly outline the pharmacology of naloxone
57%

 

96B9
Briefly explain the factors which determine the duration of effect of intravenously administered bolus doses of fentanyl.
70%

 

96A11
Describe briefly the pharmacokinetics of pethidine.
60%

 

95B9
Using opioids as examples, describe and illustrate with graphs what you understand by the terms potency, efficacy, partial agonist , competitive antagonist and therapeutic index.
70%

 

1993
Discuss the advantages and disadvantages of administering narcotics by intermittent injection or by infusion.

 

1992
Write short notes on the cardiovascular effects of narcotics

 

1991
Write short notes on  narcotics administered via the epidural route