Flow
Keypoints
For laminar flow 
- Hagen-Poiseuille equation 
i.e. Flow = Pressure x r4pi/8nl 
 - Resistance proportional to viscosity 
* Not affected by density 
 - Viscosity make laminar flow more likely
 
For turbulent flow 
- R changes with flow 
 - Resistance affected by density 
* Not affected by viscosity 
 - Density make turbulent flow more likely
 
Laminar flow
Principle
- Laminar flow occurs when stream lines of the flow are parallel to the sides of the tube 
 - Laminar flow proportional to 1/viscosity 
 - Laminar flow proportional to the 4th power for radius 
 - Axial flow moves twice as fast as mean velocity 
 - Longitudinal velocity profile is of a parabola. 
 - Density of gas is NOT relevant to laminar flow rate
 
Flow calculation
For pure laminar flow, 
--> Pressure (cmH2O) = Flow (L/sec) x Resistance 
where 
- Resistance = 8 nl/r4pi 
* n = viscosity 
* l = length 
* r = radius 
* unit = cmH2O.L-1.sec 
* unit = kPa.L-1.sec 
Hagen-Poiseuille equation
Laminar flow = Pressure x r4(pi)/8nl 
- Only applies to 
* Newtonian fluids (motion does not affect dynamic viscosity) 
* Steady flow 
* Laminar flow 
 - Blood is non-Newtonian and viscosity changes with flow
 
Turbulent flow
Principle
- Resistance is NOT constant 
* R changes with flow 
 - Pressure proportional to approx. (flow rate)2 
 - Greater resistance when flow is turbulent, everything else being equal. 
 - Pressure proportional density of gas 
 - Pressure inversely proportional to the 5th power of radius 
* i.e. Fanning equation 
 - Viscosity of gas is NOT relevant to turbulent flow rate
 
Reynold's number (Re)
Formula
Re = DV x (d/n) 
- D = diameter 
 - V = mean velocity 
 - d = density 
 - n = viscosity 
 - Dimensionless (no units)
 
Significance
- When Re>3000 
--> predominantly turbulent flow 
 - When Re<2000 
--> predominantly laminar flow  
Thus, 
- Ratio of density:viscosity (d:n) are the inherent properties of gas that contribute to Re 
 - Turbulence more likely with higher velocity and diameter
 
Additional notes
Conductance
Conductance = 1/resistance 
* Unit for conductance = L.cmH2O-1.sec-1 
Entrance length
Entrance length - the distance required for laminar flow to be established 
= 0.03 x diameter x Re 
Viscosity
Viscosity 
= ratio of shear stress to shear rate of the fluid 
Unit for viscosity 
--> dynes/cm2