However, when content increases (e.g. tumour growth)
--> Pressure increases slowly initially
* Because of translocation of CSF out of ventricles and into extracranial subarachnoid space
When this buffer is gone, then pressure increases very abruptly, as per Monro-Kelli doctrine.
By volume:
--> Increased intracranial blood volume
+ Possible increase in CSF production
--> Increase in ICP
But, CSF translocation and increased CSF resorption limits rise in ICP.
NB:
At 112mmCSF, absorption and production of CSF are roughly equal
* [WG21:p617]
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Reviewed | 20050816 |