8. Microbiology
        8.2. Gram-positive bacilli/rod
            8.2.3. Listeria
8.2.3.1. Listeria monocytogenes

Listeria Monocytogenes

Facultative, intracellular parasite

Characteristics/Epidemiology

Widespread among animals in nature

Able to grow at 4 degress celcius.

1-15% human - asymptomatic intestinal carriers

2-3% of processed diary product, 20-30% of ground meats, and majority of poultry are contaminated with L. monocytogenes.

Pathogenesis/Transmission

Transmission usually food-borne.

Infection most common in pregnant women, their foetuses, or newborn, and in immunocomprimsed persons.

Pathogenesis

Clinical significance

Listeria monocytogenes can cause:

Laboratory identification

Blood agar - small colonies with narrow zone of beta hemolysis.

(Common to all listeria) Distinguished by morphology, motility, and catalase-positivity

Treatment

First line: Ampicillin

Second line: Trimethoprim + sulfamethoxazole

Prevention/immunity

Prevention: Proper food preparation and handling


Things to revise/add later:

Bibliography: LWW microbiology


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