[WG21:p75]

Anaerobic metabolism is self-limiting due to pH drop (produced by lactate production), which limit the enzymes

 

[WG21:p78]

Duchenne's muscular dystrophy

X-linked. 1 in 3000 male. Fatal by 30 yo.

Caused by mutations in dystropin gene that cause dystrophin to be absent from the muscle.