3. Physiology
        3.12. Renal
3.12.6. Renal handling of sodium, chloride and water

Renal handling of sodium, chloride, and water

Basics

Iso-osmotic volume reabsorption

As sodium and associated solutes are reabsorbed

--> Water reabsorption by simple passive diffusion

In proximal tubule, water permeability is high

Thus,

Diffusion of water is fast enough to keep up with solute reabsorption

--> Osmolality stays unchanged

NB:

As filtrate moves down the proximal tubules,

[cf: WG21:p715]

 

 

 

 



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